A rapid, simple, high-performance liquid chromatography method for the clinical measurement of beta-lactam antibiotics in serum and interstitial fluid

Author:

Riezk Alaa1ORCID,Wilson Richard C.1,Rawson Timothy M.1,Vasikasin Vasin1,Arkel Paul1,Ferris Trevor J.2,Haigh Lisa D.2,Cass Anthony E. G.2ORCID,Holmes Alison H.1

Affiliation:

1. Centre for Antimicrobial Optimisation (CAMO), Imperial College London, Hammersmith Hospital, Du Cane Road, Acton, London, W12 0NN, UK

2. Department of Chemistry, Molecular Sciences Research Hub, Imperial College, London, UK

Abstract

A LC/MS method for the simultaneous quantitative measurement of three beta-lactam antibiotics in serum and interstitial fluid samples.

Funder

National Institute for Health Research Health Protection Research Unit

Department of Health and Social Care

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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