A low-volume LC/MS method for highly sensitive monitoring of phenoxymethylpenicillin, benzylpenicillin, and probenecid in human serum-Reference-Cited by-同舟云学术

A low-volume LC/MS method for highly sensitive monitoring of phenoxymethylpenicillin, benzylpenicillin, and probenecid in human serum

Published:2024 Issue:4 Volume:16 Page:558-565
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Riezk Alaa¹²^ORCID,Wilson Richard C.¹²³⁴,Cass Anthony E. G.²⁵^ORCID,Holmes Alison H.¹²⁴,Rawson Timothy M.¹²⁴

Affiliation:

1. National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK

2. Centre for Antimicrobial Optimisation, Imperial College London, Hammersmith Hospital, Du Cane Road, Acton, London, W12 0NN, UK

3. Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK

4. David Price Evans Infectious Diseases & Global Health Group, The University of Liverpool, Liverpool, L7 8TX, UK

5. Department of Chemistry, Molecular Sciences Research Hub, Imperial College, London, UK

Abstract

Fast and highly sensitive analysis of phenoxymethylpenicillin, benzylpenicillin and probenecid in human serum using a triple quadrupole LC/MS method for therapeutic drug monitoring.

Funder

Imperial College London

Wellcome Trust

National Institute for Health Research Health Protection Research Unit

Department of Health and Social Care

National Institute for Health and Care Research

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AY/D3AY01816D

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