The electrochemically enabled α-C(sp<sup>3</sup>)–H azolation of ketones-Reference-Cited by-同舟云学术

The electrochemically enabled α-C(sp³)–H azolation of ketones

Published:2023 Issue:76 Volume:59 Page:11425-11428
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Fang Songlin¹,Zhong Kaihui²,Zeng Shaogao¹,Hu Xinwei²,Sun Pinghua¹,Ruan Zhixiong²^ORCID

Affiliation:

1. International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education, College of Pharmacy, Jinan University, Guangzhou 510632, P. R. China

2. Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, P. R. China

Abstract

We herein reported an electrochemical synthesis of α-tetrazolyl ketones by C–H/N–H cross-coupling with excellent yields and broad substrate scope, encompassing various aryl ketones, heterocycles, and alkyl ketone drugs.

Funder

National Natural Science Foundation of China

Guangzhou Municipal Science and Technology Project

Department of Education of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC02852F

Reference44 articles.

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2. A Novel Method for Synthesis and their Antimicrobial Activity of 1H-Tetrazole Based Flavones and Flavanone Derivatives under Ultrasonic and Microwave Irradiation Methods

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4. Synthesis and in vitro evaluation of novel tetrazole embedded 1,3,5-trisubstituted pyrazoline derivatives as Entamoeba histolytica growth inhibitors

5. 5-phenyl-2H-tetrazol-2-ylmethyl ketones in the synthesis of tetrazolylalkanols and tetrazolyl(hydroxy)alkylphosphonates

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