The effect of linker length on ConA and DC-SIGN binding of S-glucosyl functionalized poly(2-oxazoline)s-Reference-Cited by-同舟云学术

The effect of linker length on ConA and DC-SIGN binding of S-glucosyl functionalized poly(2-oxazoline)s

Published:2018 Issue:5 Volume:9 Page:611-618
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Yilmaz Gokhan¹²³⁴⁵,Uzunova Veselina⁶²³⁴,Hartweg Manuel⁷⁸⁹¹⁰¹¹,Beyer Valentin⁷⁸⁹¹⁰¹¹,Napier Richard⁶²³⁴,Becer C. Remzi⁷⁸⁹¹⁰¹¹^ORCID

Affiliation:

1. Department of Chemistry

2. University of Warwick

3. CV4 7AL, Coventry

4. UK

5. Department of Basic Sciences

6. Life Sciences

7. Polymer Chemistry Laboratory

8. School of Engineering and Materials Science

9. Queen Mary

10. University of London

11. E1 4NS, London

Abstract

A series of poly(2-oxazoline) based glycopolymers with different linkers were prepared via thiol–ene click reaction and cationic ring opening reaction. The binding of these polymers to lectins were studied.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2018/PY/C7PY01939D

Reference36 articles.

1. Recent advances in the design of bioconjugates from controlled/living radical polymerization

2. Glycopolymer Nanobiotechnology

3. The Glycopolymer Code: Synthesis of Glycopolymers and Multivalent Carbohydrate-Lectin Interactions

4. Glycopolymer probes of signal transduction

5. Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN

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