Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN-Reference-Cited by-同舟云学术

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Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN

Published:2017 Issue:10 Volume:8 Page:6974-6980
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Mitchell Daniel A.¹²³⁴⁵,Zhang Qiang⁶²⁷⁴,Voorhaar Lenny⁶²⁷⁴,Haddleton David M.⁶²⁷⁴^ORCID,Herath Shan⁸⁹¹⁰⁴,Gleinich Anne S.¹²³⁴,Randeva Harpal S.¹²³⁴⁵,Crispin Max¹¹¹²¹³⁴,Lehnert Hendrik¹⁴¹⁵¹⁶,Wallis Russell¹⁷¹⁸¹⁹⁴,Patterson Steven⁸⁹¹⁰⁴,Becer C. Remzi²⁰²¹²²⁴^ORCID

Affiliation:

1. Clinical Sciences Research Laboratories

2. University of Warwick

3. Coventry CV2 2DX

4. United Kingdom

5. University Hospital Coventry

6. Department of Chemistry

7. Coventry CV4 7AL

8. Chelsea & Westminster Hospital

9. Imperial College School of Medicine

10. London SW10 9NH

11. Glycobiology Institute

12. University of Oxford

13. Oxford OX1 3QU

14. Universität zu Lübeck

15. 23562 Lübeck

16. Germany

17. Department of Biochemistry

18. University of Leicester

19. Leicester LE1 9HN

20. School of Engineering and Materials Science

21. Queen Mary University

22. London E1 4NS

Abstract

Dendritic cells bridge the innate and adaptive immune systems and they can be manipulated by star shaped glycopolymers.

Funder

Engineering and Physical Sciences Research Council

H2020 Excellent Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC01515A

Reference25 articles.

1. Pathogens use carbohydrates to escape immunity induced by dendritic cells

2. Activated Apoptotic Cells Induce Dendritic Cell Maturation via Engagement of Toll-like Receptor 4 (TLR4), Dendritic Cell-specific Intercellular Adhesion Molecule 3 (ICAM-3)-grabbing Nonintegrin (DC-SIGN), and β2 Integrins

3. Structure–Function Analysis of C-Type Animal Lectins

4. DC-SIGN, a Dendritic Cell–Specific HIV-1-Binding Protein that Enhances trans-Infection of T Cells

5. Mycobacteria Target DC-SIGN to Suppress Dendritic Cell Function

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3. Design of Glycopolymers for Controlling the Interactions with Lectins;Chemistry – An Asian Journal;2023-09-04

4. Water-soluble PEG segmented mannose-based macromolecules: Synthesis, characterization and their biocompatibility;International Journal of Biological Macromolecules;2023-05

5. Glycopolymers based on carbohydrate or vinyl backbones and their biomedical applications;Polymer Chemistry;2023

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