Robust oil-core nanocapsules with hyaluronate-based shells as promising nanovehicles for lipophilic compounds

Author:

Szafraniec Joanna12345,Błażejczyk Agnieszka67894,Kus Edyta102114,Janik Małgorzata1234,Zając Gabriela1234,Wietrzyk Joanna67894,Chlopicki Stefan10211412,Zapotoczny Szczepan1234ORCID

Affiliation:

1. Faculty of Chemistry

2. Jagiellonian University

3. 30-387 Krakow

4. Poland

5. Department of Pharmaceutical Technology and Biopharmaceutics

6. Laboratory of Experimental Oncology

7. Ludwik Hirszfeld Institute of Immunology and Experimental Therapy

8. Polish Academy of Sciences

9. 53-114 Wroclaw

10. Jagiellonian Centre for Experimental Therapeutics (JCET)

11. 30-348 Krakow

12. Chair of Pharmacology

Abstract

Biocompatible hyaluronate-based nanocapsules with liquid oil cores exhibiting long-term stability and tunable size were obtained in a versatile surfactant-free process and their biodistribution was studied in vivo and in vitro.

Funder

Ministerstwo Nauki i Szkolnictwa Wyższego

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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