Cell-free and cytokine-free self-assembling peptide hydrogel-polycaprolactone composite scaffolds for segmental bone defects-Reference-Cited by-同舟云学术

Cell-free and cytokine-free self-assembling peptide hydrogel-polycaprolactone composite scaffolds for segmental bone defects

Published:2023 Issue:3 Volume:11 Page:840-853
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Wu Tong¹,Wu Yilun¹,Cao Zhicheng²,Zhao Lulu³,Lv Jiayi¹,Li Jiayi²,Xu Yue³,Zhang Po²,Liu Xu¹,Sun Yuzhi²,Cheng Min¹,Tang Kexin³,Jiang Xiao²,Ling Chen²,Yao Qingqiang²,Zhu Yishen¹^ORCID

Affiliation:

1. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 211816, Nanjing, China

2. Department of Orthopaedic Surgery, Institute of Digital Medicine, Nanjing First Hospital, Nanjing Medical University, 210006, Nanjing, China

3. College of Pharmaceutical Sciences, Nanjing Tech University, 211816, Nanjing, China

Abstract

An ECM-mimetic peptide hydrogel was infilled into a 3D-printed PCL scaffold, forming unique nano- and micro-morphology and endowing osteogenesis. This scaffold was employed for a segmental ulna defect repair in rabbits, with bioinformatic analysis.

Funder

National Natural Science Foundation of China

Jiangsu Provincial Key Research and Development Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D2BM01609E

Reference52 articles.

1. Treatments, cost and healthcare utilization of patients with segmental bone defects

2. Recent Research on Hybrid Hydrogels for Infection Treatment and Bone Repair