Continuous-flow thermolysis for the preparation of vinylglycine derivatives
Author:
Affiliation:
1. Center for Integrated Technology and Organic Synthesis
2. Department of Chemistry
3. University of Liège
4. 4000 Liège
5. Belgium
6. Cyclotron Research Centre
Abstract
The continuous-flow thermolysis of methionine sulfoxide derivatives in superheated toluene enabled the convenient, high-yielding and selective production of vinylglycine derivatives.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB02036K
Reference64 articles.
1. α-Vinylic amino acids: occurrence, asymmetric synthesis, and biochemical mechanisms
2. Synthesis of .beta.,.gamma.-unsaturated amino acids
3. L-Vinylglycine
4. N-(Benzyloxycarbonyl)-L-vinylglycike Methyl Ester from L-Methionine Methyl Ester Hydrochloride
5. A photochemical route to vinylglycine and a vinylglycine dipeptide
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