Perilla seed oil in combination with nobiletin-rich ponkan powder enhances cognitive function in healthy elderly Japanese individuals: a possible supplement for brain health in the elderly

Author:

Hashimoto Michio1ORCID,Matsuzaki Kentaro1ORCID,Maruyama Koji2,Hossain Shahdat3ORCID,Sumiyoshi Eri1ORCID,Wakatsuki Harumi1,Kato Setsushi4,Ohno Miho4,Tanabe Yoko1,Kuroda Yoko5,Yamaguchi Shuhei6,Kajima Koji2,Ohizumi Yasushi7,Shido Osamu1

Affiliation:

1. Department of Environmental Physiology, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan

2. Sankyo Holdings Co., Ltd, Fuji, Shizuoka, Japan

3. Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka, Bangladesh

4. Kato Hospital, Jinjukai Healthcare Corporation, Kawamoto, Shimane, Japan

5. Department of Internal Medicine III, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan

6. Shimane Prefecture Hospital Bureau, Izumo, Shimane, Japan

7. Kansei Fukushi Research Institute, Tohoku Fukushi University, Sendai, Miyagi, Japan

Abstract

Long-term intake of encapsulated perilla seed oil + immature ponkan powder enhances serum BDNF and antioxidant potential, and may improve age-related cognitive decline in healthy elderly Japanese by increasing red blood cell ω-3 fatty acid levels.

Funder

Shimane University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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