Pyrene-labeled pyrrolidinyl peptide nucleic acid as a hybridization-responsive DNA probe: comparison between internal and terminal labeling-Reference-Cited by-同舟云学术

Pyrene-labeled pyrrolidinyl peptide nucleic acid as a hybridization-responsive DNA probe: comparison between internal and terminal labeling

Published:2014 Issue:17 Volume:4 Page:8817-8827
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Boonlua Chalothorn¹²³⁴⁵,Ditmangklo Boonsong¹²³⁴⁵,Reenabthue Nisanath²³⁶⁷,Suparpprom Chaturong²³⁶⁷,Poomsuk Nattawee⁸²³⁹¹⁰,Siriwong Khatcharin⁸²³⁹¹⁰,Vilaivan Tirayut¹²³⁴⁵

Affiliation:

1. Organic Synthesis Research Unit

2. Department of Chemistry

3. Faculty of Science

4. Chulalongkorn University

5. Bangkok 10330, Thailand

6. Naresuan University

7. Phitsanulok 65000, Thailand

8. Materials Chemistry Research Unit

9. Khon Kaen University

10. Khon Kaen 40002, Thailand

Abstract

Internally pyrene-labeled pyrrolidinyl PNA yields much larger fluorescence increase than terminally labeled PNA upon hybridization with complementary DNA.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C3RA47997H

Reference55 articles.

1. Molecular Beacons: Probes that Fluoresce upon Hybridization

2. Multicolor molecular beacons for allele discrimination

3. Interactive Fluorophore and Quencher Pairs for Labeling Fluorescent Nucleic Acid Hybridization Probes

4. Fluorescent hybridization probes for nucleic acid detection

5. Fluorescence based strategies for genetic analysis

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