Formic acid as a sustainable and complementary reductant: an approach to fused benzimidazoles by molecular iodine-catalyzed reductive redox cyclization of o-nitro-t-anilines-Reference-Cited by-同舟云学术

Formic acid as a sustainable and complementary reductant: an approach to fused benzimidazoles by molecular iodine-catalyzed reductive redox cyclization of o-nitro-t-anilines

Published:2016 Issue:10 Volume:18 Page:2966-2970
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Nguyen T. B.¹²³⁴,Ermolenko L.¹²³⁴,Al-Mourabit A.¹²³⁴

Affiliation:

1. Institut de Chimie des Substances Naturelles - CNRS-ICSN UPR 2301

2. Université Paris-Sud

3. 91198 Gif-sur-Yvette Cedex

4. France

Abstract

Molecular iodine was found to be an excellent catalyst for reductive redox cyclization of o-nitro-t-anilines 1 into fused tricyclic or 1,2-disubtituted benzimidazoles 2.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/GC/C6GC00902F

Reference38 articles.

1. Discovery of a Novel, Efficient, and Scalable Route to Bendamustine Hydrochloride: The API in Treanda

2. Improved Continuous Flow Processing: Benzimidazole Ring Formation via Catalytic Hydrogenation of an Aromatic Nitro Compound

3. Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. part 4: Biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries

4. Synthesis and biological evaluation of 1H-benzimidazol-5-ols as potent HBV inhibitors

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