Palladium-catalyzed direct C–H ethoxycarbonylation of 2-aryl-1,2,3-triazoles and efficient synthesis of suvorexant-Reference-Cited by-同舟云学术

Palladium-catalyzed direct C–H ethoxycarbonylation of 2-aryl-1,2,3-triazoles and efficient synthesis of suvorexant

Published:2018 Issue:4 Volume:5 Page:648-652
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Sang Rui¹²³⁴⁵,Zheng Yang¹²³⁴⁵,Zhang Hailong¹²³⁴⁵,Wu Xiaohua¹²³⁴⁵,Wang Qiantao¹²³⁴⁵,Hai Li¹²³⁴⁵,Wu Yong¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education

2. West China School of Pharmacy

3. Sichuan University

4. Chengdu 610041

5. China

Abstract

Palladium-catalyzed direct ethoxycarbonylation with diethyl azodicarboxylate was developed and its reaction mechanism was explored by using DFT calculations.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C7QO00945C

Reference36 articles.

1. Human β3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides

2. Discovery of the Dual Orexin Receptor Antagonist [(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia

3. The First Large-Scale Synthesis of MK-4305: A Dual Orexin Receptor Antagonist for the Treatment of Sleep Disorder

4. Novel pyrrole- and 1,2,3-triazole-based 2,3-oxidosqualene cyclase inhibitors

5. Orexin Receptor Antagonists: New Therapeutic Agents for the Treatment of Insomnia

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Rhodium-catalysed additive-free alkoxycarbonylation of indoles: 2,4,6-trimethylbenzoic acid-based carbonate anhydrides as a versatile alkoxycarboxyl source;Organic & Biomolecular Chemistry;2024

2. Direct access to carbamates via acylation of arylamines with dialkyl azodicarboxylates under metal-free conditions;Organic & Biomolecular Chemistry;2023

3. CO free esterifications of (Hetero)arenes via transition-metal-catalyzed chelation-induced C–H activation: Recent updates;Tetrahedron;2022-01

4. Rhodium‐Catalyzed Additive‐Free C−H Ethoxycarbonylation of (Hetero)Arenes with Diethyl Dicarbonate as a CO Surrogate;European Journal of Organic Chemistry;2021-09-15

5. Base‐Promoted Regiospecific Synthesis of Fully Substituted 1,2,3‐Triazoles and 1,5‐Disubstituted 1,2,3‐Triazoles;Asian Journal of Organic Chemistry;2020-11-04