Influence of conjugation and other structural changes on the activity of Cu2+ based PNAzymes-Reference-Cited by-同舟云学术

Influence of conjugation and other structural changes on the activity of Cu2+ based PNAzymes

Published:2016 Issue:9 Volume:14 Page:2768-2773
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ghidini A.¹²³⁴,Murtola M.¹²³⁴⁵,Strömberg R.¹²³⁴

Affiliation:

1. Karolinska Institutet

2. Department of Biosciences and Nutrition

3. S-14183 Huddinge

4. Sweden

5. Turku University

Abstract

Neocuproine based PNAzymes with further conjugated entities as well as constructs clamping the target RNA to form a triplex are reported. This extends the arsenal of PNAzymes as efficient artificial RNA restriction nucleases.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB02394G

Reference38 articles.

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