The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP-Reference-Cited by-同舟云学术

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

Published:2012-11-11 Issue:7427 Volume:492 Page:123-127
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Lee Geun-Shik,Subramanian Naeha,Kim Andrew I.,Aksentijevich Ivona,Goldbach-Mansky Raphaela,Sacks David B.,Germain Ronald N.,Kastner Daniel L.,Chae Jae Jin

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature11588.pdf

Reference24 articles.

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2. Kahlenberg, J. M. & Dubyak, G. R. Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. Am. J. Physiol. Cell Physiol. 286, C1100–C1108 (2004)

3. Zhou, R., Tardivel, A., Thorens, B., Choi, I. & Tschopp, J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nature Immunol. 11, 136–140 (2010)

4. Hornung, V. et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nature Immunol. 9, 847–856 (2008)

5. Pétrilli, V. et al. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14, 1583–1589 (2007)

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