Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization-Reference-Cited by-同舟云学术

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Published:2008-07-11 Issue:8 Volume:9 Page:847-856
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Hornung Veit,Bauernfeind Franz,Halle Annett,Samstad Eivind O,Kono Hajime,Rock Kenneth L,Fitzgerald Katherine A,Latz Eicke

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.1631.pdf

Reference40 articles.

1. Mossman, B.T. & Churg, A. Mechanisms in the pathogenesis of asbestosis and silicosis. Am. J. Respir. Crit. Care Med. 157, 1666–1680 (1998).

2. Huaux, F. New developments in the understanding of immunology in silicosis. Curr. Opin. Allergy Clin. Immunol. 7, 168–173 (2007).

3. Martinon, F., Petrilli, V., Mayor, A., Tardivel, A. & Tschopp, J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440, 237–241 (2006).

4. Petrilli, V., Dostert, C., Muruve, D.A. & Tschopp, J. The inflammasome: a danger sensing complex triggering innate immunity. Curr. Opin. Immunol. 19, 615–622 (2007).

5. Agostini, L. et al. NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20, 319–325 (2004).

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