Poly(zwitterionic)protein conjugates offer increased stability without sacrificing binding affinity or bioactivity
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/nchem.1213.pdf
Reference24 articles.
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3. Fishburn, C. S. The pharmacology of PEGylation: balancing PD with PK to generate novel therapeutics. J. Pharm. Sci. 97, 4167–4183 (2008).
4. Veronese, F. M. Peptide and protein PEGylation: a review of problems and solutions. Biomaterials 22, 405–417 (2001).
5. Shaunak, S. et al. Site-specific PEGylation of native disulfide bonds in therapeutic proteins. Nature Chem. Biol. 2, 312–313 (2006).
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