The hypoxia‐inducible‐factor hydroxylases bring fresh air into hypoxia signalling
Author:
Affiliation:
1. Institute of Signalling, Developmental Biology and Cancer Research, CNRS UMR‐6543, University of Nice, Centre Antoine Lacassagne 33 Avenue Valombrose Nice 06189 France
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1038/sj.embor.7400598
Reference44 articles.
1. Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
2. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors
3. OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1α
4. HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1α degradation
5. Hypoxia‐inducible factor‐1α (HIF‐1α) escapes O2‐driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm
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