OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1α-Reference-Cited by-同舟云学术

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OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1α

Published:2005-02 Issue:4 Volume:17 Page:503-512
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Baek Jin Hyen,Mahon Patrick C.,Oh Jane,Kelly Brian,Krishnamachary Balaji,Pearson Mia,Chan Denise A.,Giaccia Amato J.,Semenza Gregg L.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference41 articles.

1. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia;Berra;EMBO J.,2003

2. A conserved family of prolyl-4-hydroxylases that modify HIF;Bruick;Science,2001

3. Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1α;Chan;J. Biol. Chem.,2002

4. Hypoxia up-regulates prolyl hydroxylase activity;D'Angelo;J. Biol. Chem.,2003

5. Structure of factor inhibiting hypoxia-inducible factor 1;Dann;Proc. Natl. Acad. Sci. USA,2002

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