Crosstalk between the Akt/mTORC1 and NF-κB signaling pathways promotes hypoxia-induced pulmonary hypertension by increasing DPP4 expression in PASMCs-Reference-Cited by-同舟云学术

Crosstalk between the Akt/mTORC1 and NF-κB signaling pathways promotes hypoxia-induced pulmonary hypertension by increasing DPP4 expression in PASMCs

Published:2019-07-17 Issue:10 Volume:40 Page:1322-1333
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Li Ying,Yang Li,Dong Liang,Yang Zhi-wei,Zhang Jing,Zhang Sheng-li,Niu Meng-jie,Xia Jing-wen,Gong Yi,Zhu Ning,Zhang Xiu-juan,Zhang Yuan-yuan,Wei Xiao-min,Zhang You-zhi,Zhang Peng,Li Sheng-qing

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/s41401-019-0272-2.pdf

Reference44 articles.

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2. Voelkel NF, Tamosiuniene R, Nicolls MR. Challenges and opportunities in treating inflammation associated with pulmonary hypertension. Expert Rev Cardiovasc Ther. 2016;14:939–51.

3. Paulin R, Meloche J, Courboulin A, Lambert C, Haromy A, Courchesne A, et al. Targeting cell motility in pulmonary arterial hypertension. Eur Respir J. 2014;43:531–44.

4. Wang AP, Li XH, Yang YM, Li WQ, Zhang W, Hu CP, et al. A critical role of the mTOR/eIF2alpha pathway in hypoxia-induced pulmonary hypertension. PLoS ONE. 2015;10:e0130806.

5. Ma X, Yao J, Yue Y, Du S, Qin H, Hou J, et al. Rapamycin reduced pulmonary vascular remodelling by inhibiting cell proliferation via Akt/mTOR signalling pathway down-regulation in the carotid artery-jugular vein shunt pulmonary hypertension rat model. Interact Cardiovasc Thorac Surg. 2017;25:206–11.

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