DNA-binding-domain fusions enhance the targeting range and precision of Cas9-Reference-Cited by-同舟云学术

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DNA-binding-domain fusions enhance the targeting range and precision of Cas9

Published:2015-10-19 Issue:12 Volume:12 Page:1150-1156
ISSN:1548-7091
Container-title:Nature Methods
language:en
Short-container-title:Nat Methods

Author:

Bolukbasi Mehmet Fatih,Gupta Ankit,Oikemus Sarah,Derr Alan G,Garber Manuel,Brodsky Michael H,Zhu Lihua Julie,Wolfe Scot A

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Biochemistry,Biotechnology

Link

http://www.nature.com/articles/nmeth.3624.pdf

Reference63 articles.

1. Doudna, J.A. & Charpentier, E. Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science 346, 1258096 (2014).

2. Sander, J.D. & Joung, J.K. CRISPR-Cas systems for editing, regulating and targeting genomes. Nat. Biotechnol. 32, 347–355 (2014).

3. Hsu, P.D., Lander, E.S. & Zhang, F. Development and applications of CRISPR-Cas9 for genome engineering. Cell 157, 1262–1278 (2014).

4. Jinek, M. et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816–821 (2012).

5. Sternberg, S.H., Redding, S., Jinek, M., Greene, E.C. & Doudna, J.A. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9. Nature 507, 62–67 (2014).

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