The combination of ruxolitinib and Bcl-2/Mcl-1 inhibitors has a synergistic effect on leukemic cells carrying a SPAG9::JAK2 fusion-Reference-Cited by-同舟云学术

The combination of ruxolitinib and Bcl-2/Mcl-1 inhibitors has a synergistic effect on leukemic cells carrying a SPAG9::JAK2 fusion

Published:2022-07-25 Issue:12 Volume:29 Page:1930-1938
ISSN:0929-1903
Container-title:Cancer Gene Therapy
language:en
Short-container-title:Cancer Gene Ther

Author:

Mayumi Azusa,Tomii Toshihiro,Kanayama Takuyo^ORCID,Mikami Takashi^ORCID,Tanaka Kuniaki,Ueno Hiroo,Yoshida Hideki,Kato Itaru^ORCID,Kawamura Machiko,Nakahata Tatsutoshi,Takita Junko^ORCID,Hosoi Hajime,Imamura Toshihiko^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Link

https://www.nature.com/articles/s41417-022-00511-z.pdf

Reference24 articles.

1. Tasian SK, Loh ML, Hunger SP. Philadelphia chromosome-like acute lymphoblastic leukemia. Blood. 2017;130:2064–72.

2. Roberts KG, Gu Z, Payne-Turner D, McCastlain K, Harvey RC, Chen IM, et al. High frequency and poor outcome of philadelphia chromosome-like acute lymphoblastic leukemia in adults. J Clin Oncol. 2017;35:394–401.

3. Kawamura M, Taki T, Kaku H, Ohki K, Hayashi Y. Identification of SPAG9 as a novel JAK2 fusion partner gene in pediatric acute lymphoblastic leukemia with t(9;17)(p24;q21). Genes Chromosomes Cancer. 2015;54:401–8.

4. Reshmi SC, Harvey RC, Roberts KG, Stonerock E, Smith A, Jenkins H, et al. Targetable kinase gene fusions in high-risk B-ALL: a study from the Children’s Oncology Group. Blood. 2017;129:3352–61.

5. Schinnerl D, Fortschegger K, Kauer M, Marchante JR, Kofler R, Den Boer ML, et al. The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia. Blood. 2015;125:1282–91.

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