A role for fMRI in optimizing CNS drug development
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2027.pdf
Reference152 articles.
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3. Frank, R. & Hargreaves, R. Clinical biomarkers in drug discovery and development. Nature Rev. Drug Discov. 2, 566?580 (2003). Biomarkers will become highly valued processes to characterize drugs and disease states.
4. Pritchard, J. F. et al. Making better drugs: Decision gates in non-clinical drug development. Nature Rev. Drug Discov. 2, 542?553 (2003).
5. Bleicher, K. H., Bohm, H. J., Muller, K. & Alanine, A. I. Hit and lead generation: beyond high-throughput screening. Nature Rev. Drug Discov. 2, 369?378 (2003).
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