Hit and lead generation: beyond high-throughput screening-Reference-Cited by-同舟云学术

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Hit and lead generation: beyond high-throughput screening

Published:2003-05 Issue:5 Volume:2 Page:369-378
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Bleicher Konrad H.,Böhm Hans-Joachim,Müller Klaus,Alanine Alexander I.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd1086.pdf

Reference44 articles.

1. Drews, J. Drug discovery: A historical perspective. Science 287, 1960–1964 (2000).

2. Lander, E. S. et al. Initial sequencing and analysis of the human genome. Nature 409, 860–921 (2001).

3. Knowles, J. & Gromo, G. Target selection in drug discovery. Nature Rev. Drug Discov. 2, 63–69 (2003).

4. Hopkins, A. L. & Groom, C. R. The druggable genome. Nature Rev. Drug Discov. 1, 727–730 (2002).

5. Lenz, G. R., Nash, H. M. & Jindal, A. Chemical ligands, genomics and drug discovery. Drug Discov. Today 5, 145–156 (2000).

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