Systematic analysis reveals the prevalence and principles of bypassable gene essentiality
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-08928-1.pdf
Reference70 articles.
1. Juhas, M., Eberl, L. & Church, G. M. Essential genes as antimicrobial targets and cornerstones of synthetic biology. Trends Biotech. 30, 601–607 (2012).
2. Zhan, T. & Boutros, M. Towards a compendium of essential genes—from model organisms to synthetic lethality in cancer cells. Crit. Rev. Biochem. Mol. Biol. 51, 74–85, (2016).
3. Dowell, R. D. et al. Genotype to phenotype: a complex problem. Science 328, 469, (2010).
4. Blomen, V. A. et al. Gene essentiality and synthetic lethality in haploid human cells. Science 350, 1092–1096, (2015).
5. Hart, T. et al. High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities. Cell 163, 1515–1526 (2015).
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