RNA-seq reveals the critical role of OtpR in regulating Brucella melitensis metabolism and virulence under acidic stress
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep10864.pdf
Reference61 articles.
1. DelVecchio, V. G. et al. The genome sequence of the facultative intracellular pathogen Brucella melitensis. Proc Natl Acad Sci U S A 99, 443–448. (2002).
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3. Phillips, R. W. & Roop, R. M., 2nd Brucella abortus HtrA functions as an authentic stress response protease but is not required for wild-type virulence in BALB/c mice. Infect Immun 69, 5911–5913 (2001).
4. Porte, F., Liautard, J. P. & Kohler, S. Early acidification of phagosomes containing Brucella suis is essential for intracellular survival in murine macrophages. Infect Immun 67, 4041–4047. (1999).
5. Zhang, X., Ren, J., Li, N., Liu, W. & Wu, Q. Disruption of the BMEI0066 gene attenuates the virulence of Brucella melitensis and decreases its stress tolerance. Int J Biol Sci 5, 570–577 (2009).
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