A Mechanistic, Model-Based Approach to Safety Assessment in Clinical Development-Reference-Cited by-同舟云学术

A Mechanistic, Model-Based Approach to Safety Assessment in Clinical Development

Published:2012-11 Issue:11 Volume:1 Page:13
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT: Pharmacometrics & Systems Pharmacology

Author:

Lippert J¹,Brosch M²,von Kampen O²,Meyer M¹,Siegmund H.-U¹,Schafmayer C³,Becker T³,Laffert B⁴,Görlitz L¹,Schreiber S²,Neuvonen PJ⁵⁶,Niemi M⁵⁶,Hampe J²,Kuepfer L¹

Affiliation:

1. Computational Systems Biology, Bayer Technology Services GmbH; Leverkusen Germany

2. Department of Internal Medicine I; University Hospital Schleswig-Holstein, Campus Kiel, Christian-Albrechts-University; Kiel Germany

3. Department of General and Thoracic Surgery; University Hospital Schleswig-Holstein, Campus Kiel, Christian-Albrechts-University; Kiel Germany

4. Cell Culture Service; Hamburg Germany

5. Department of Clinical Pharmacology; University of Helsinki; Helsinki Finland

6. HUSLAB, Helsinki University Central Hospital; Helsinki Finland

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1038/psp.2012.14/fullpdf

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