Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction-Reference-Cited by-同舟云学术

Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction

Author:

Prieto Garcia Luna¹²^ORCID,Lundahl Anna³^ORCID,Ahlström Christine²,Vildhede Anna²^ORCID,Lennernäs Hans¹^ORCID,Sjögren Erik¹^ORCID

Affiliation:

1. Department of Pharmaceutical Bioscience, Translational Drug Discovery and Development Uppsala University Uppsala Sweden

2. DMPK, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D AstraZeneca Gothenburg Sweden

3. Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D AstraZeneca Gothenburg Sweden

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

Reference49 articles.

4. EMEA (ed Committee for Medical Products for Human Use [CHMP]).2018.

5. FDA (ed U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research [CDER]).2018.

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