Physiological‐based pharmacokinetic modeling trends in pharmaceutical drug development over the last 20‐years; in‐depth analysis of applications, organizations, and platforms
Author:
Affiliation:
1. Centre for Applied Pharmacokinetic Research University of Manchester Manchester UK
2. Clinical Pharmacy Department Faculty of Pharmacy Tanta University Tanta Egypt
3. Certara UK Limited Sheffield UK
Funder
University of Manchester
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bdd.2257
Reference39 articles.
1. IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies
2. Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?
3. IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes
4. A computational systems biology software platform for multiscale modeling and simulation: Integrating whole‐body physiology, disease biology, and molecular reaction networks;Eissing T.;Frontiers in Physiology,2011
Cited by 82 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A physiologically based pharmacokinetic model of voriconazole in human CNS—Integrating time-dependent inhibition of CYP3A4, genetic polymorphisms of CYP2C19 and possible transporter mechanisms;International Journal of Antimicrobial Agents;2024-10
2. Application of physiologically based pharmacokinetic modeling of novel drugs approved by the U.S. food and drug administration;European Journal of Pharmaceutical Sciences;2024-09
3. A physiologically‐based pharmacokinetic modeling approach for dosing amiodarone in children on ECMO;CPT: Pharmacometrics & Systems Pharmacology;2024-07-21
4. A guide to developing population files for physiologically‐based pharmacokinetic modeling in the Simcyp Simulator;CPT: Pharmacometrics & Systems Pharmacology;2024-07-18
5. Applying quantitative and systems pharmacology to drug development and beyond: An introduction to clinical pharmacologists;Indian Journal of Pharmacology;2024-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3