Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?

Author:

Bouzom François1,Ball Kathryn1,Perdaems Nathalie1,Walther Bernard1

Affiliation:

1. Technologie Servier; 25/27 rue E. Vignat; 45000; Orleans; France

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference59 articles.

1. The FDA website http://fda.gov/AboutFDA/Transparency/Basics/ 2011

2. A knoll by Krishan Maggon http://knol.google.com/k/krishan-maggon/new-drug-approvals_fda_ema_2011/ 2011

3. The Boeing website http://www.boeing.com/history/boeing/777.html 2011

4. Relevance of the application of pharmacokinetic-pharmacodynamic modelling concepts in drug development. The ‘wooden shoe’ paradigm;Breimer;Clin Pharmacokinet,1997

5. Optimizing the science of drug development opportunities for better candidate selection and accelerated evaluation in humans;Lesko;Eur J Pharm Sci,2000

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