Physiologically based pharmacokinetic modeling in drug discovery and development: A pharmaceutical industry perspective

Author:

Jones HM1,Chen Y2,Gibson C3,Heimbach T4,Parrott N5,Peters SA6,Snoeys J7,Upreti VV8,Zheng M9,Hall SD10

Affiliation:

1. Pfizer Worldwide Research & Development; Cambridge Massachusetts USA

2. Genentech; South San Francisco California USA

3. Merck Research Laboratories; West Point Pennsylvania USA

4. Novartis Institutes for Biomedical Research; East Hanover New Jersey USA

5. F. Hoffmann-La Roche Ltd; Basel Switzerland

6. Astrazeneca Research & Development; Mölndal Sweden

7. Janssen Research & Development; Beerse Belgium

8. Amgen; Seattle Washington USA

9. Bristol Myers Squibb Company; Pennington New Jersey USA

10. Eli Lily & Company; Indianapolis Indiana USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference75 articles.

1. Kinetics of distribution of substances administered to the body. I. The extravascular modes of administration;Teorell;Arch. Int. Pharmacodyn. Ther,1937

2. Drug interaction guideline for drug development and labeling recommendations (draft) 2014

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