Phospholipase D2 loss results in increased blood pressure via inhibition of the endothelial nitric oxide synthase pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-09852-4.pdf
Reference50 articles.
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2. Frohman, M. A. The phospholipase D superfamily as therapeutic targets. Trends in pharmacological sciences 36, 137–144, doi: 10.1016/j.tips.2015.01.001 (2015).
3. Elvers, M. et al. Impaired alpha(IIb)beta(3) integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1. Science signaling 3, ra1, doi: 10.1126/scisignal.2000551 (2010).
4. Stegner, D. et al. Pharmacological inhibition of phospholipase D protects mice from occlusive thrombus formation and ischemic stroke–brief report. Arteriosclerosis, thrombosis, and vascular biology 33, 2212–2217, doi: 10.1161/atvbaha.113.302030 (2013).
5. Chen, Q. et al. Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis. Science signaling 5, ra79, doi: 10.1126/scisignal.2003257 (2012).
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