Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-18598-y.pdf
Reference18 articles.
1. Martin, J. R. & Arici, A. Fragile X and reproduction. Curr Opin Obstet Gynecol 20, 216–220 (2008).
2. Hoffman, G. E. et al. Ovarian abnormalities in a mouse model of fragile X primary ovarian insufficiency. J Histochem Cytochem 60, 439–56 (2012).
3. Bachner, D. et al. Enhanced expression of the murine FMR1 gene during germ cell proliferation suggests a special function in both the male and female gonad. Hum Mol Genet 2, 2043–50 (1993).
4. Rife, M., Nadal, A., Mila, M. & Willemsen, R. Immunohistochemical FMRP studies in a full mutated female fetus. Am J Med Genet 124A, 129–132 (2004).
5. Wittenberger, M. D. et al. The FMR1 premutation and reproduction. Fertil Steril 87, 456–465 (2007).
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