Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use-Reference-Cited by-同舟云学术

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Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use

Published:2019-02-20 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Ishikawa Masaaki^ORCID,García-Mateo Nadia,Čusak Alen,López-Hernández Iris,Fernández-Martínez Marta,Müller Marcus,Rüttiger Lukas,Singer Wibke,Löwenheim Hubert,Kosec Gregor,Fujs Štefan,Martínez-Martínez Luis,Schimmang Thomas,Petković Hrvoje,Knipper Marlies,Durán-Alonso M. Beatriz^ORCID

Funder

Deutsche Forschungsgemeinschaft

TRIH grants / Action on Hearing Loss

Acies Bio d.o.o

TRIH Action and Hearing Loss, T3 Petkovic

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-38634-3.pdf

Reference84 articles.

1. Maura, D., Ballok, A. E. & Rahme, L. G. Considerations and caveats in anti-virulence drug development. Current opinion in microbiology 33, 41–46, https://doi.org/10.1016/j.mib.2016.06.001 (2016).

2. Tacconelli, E. et al. Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. The Lancet. Infectious diseases 18, 318–327, https://doi.org/10.1016/S1473-3099(17)30753-3 (2018).

3. Forge, A. & Schacht, J. Aminoglycoside antibiotics. Audiol Neurootol 5, 3–22, 13861 (2000).

4. Huth, M. E., Ricci, A. J. & Cheng, A. G. Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection. Int J Otolaryngol 2011, 937861, https://doi.org/10.1155/2011/937861 (2011).

5. Cooper, M. A. & Shlaes, D. Fix the antibiotics pipeline. Nature 472, 32, https://doi.org/10.1038/472032a (2011).

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