Apramycin efficacy against carbapenem- and aminoglycoside-resistant Escherichia coli and Klebsiella pneumoniae in murine bloodstream infection models
Author:
Funder
Innovative Medicines Initiative
Publisher
Elsevier BV
Reference22 articles.
1. European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European Society of Intensive Care Medicine);Paul;Clin Microbiol Infect,2022
2. Molecular identification of aminoglycoside-modifying enzymes in clinical isolates of Escherichia coli resistant to amoxicillin/clavulanic acid isolated in Spain;Fernández-Martínez;Int J Antimicrob Agents,2015
3. Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose;Zhao;J Antimicrob Chemother,2022
4. Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin;Matt;Proc Natl Acad Sci U S A,2012
5. Evaluation of apramycin activity against carbapenem-resistant and -susceptible strains of Enterobacteriaceae;Smith;Diagn Microbiol Infect Dis,2016
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