Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers

Author:

Shi Xuan,Miyakawa Takuya,Nakamura AkiraORCID,Hou Feng,Hibi MakotoORCID,Ogawa Jun,Kwon Yeondae,Tanokura MasaruORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference60 articles.

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3. Xue, W. L. et al. Effect of Trigonella foenum-graecum (fenugreek) extract on blood glucose, blood lipid and hemorheological properties in streptozotocin-induced diabetic rats. Asia Pac. J. Clin. Nutr. 16, 422–426 (2007).

4. Zia, T., Hasnain, S. N. & Hasan, S. K. Evaluation of the oral hypoglycaemic effect of Trigonella foenum-graecum L. (methi) in normal mice. J. Ethnopharmacol. 75, 191–195 (2001).

5. Stark, A. & Madar, Z. The effect of an ethanol extract derived from fenugreek (Trigonella foenum-graecum) on bile acid absorption and cholesterol levels in rats. Br. J. Nutr. 69, 277–287 (1993).

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