Structure and Cooperativity in Substrate–Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design-Reference-Cited by-同舟云学术

Structure and Cooperativity in Substrate–Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design

Published:2022-01-18 Issue:2 Volume:17 Page:266-280
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Rajakumara Eerappa¹^ORCID,Abhishek Suman¹^ORCID,Nitin Kulhar¹,Saniya Dubey¹,Bajaj Priyanka²,Schwaneberg Ulrich³⁴^ORCID,Davari Mehdi D.⁵^ORCID

Affiliation:

1. Macromolecular Structural Biology Lab, Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana 502285, India

2. National Institute of Pharmaceutical Education and Research (NIPER), NH-44, Balanagar, Hyderabad 500037, India

3. Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074 Aachen, Germany

4. DWI-Leibniz Institute for Interactive Materials, Forckenbeckstraße 50, 52074 Aachen, Germany

5. Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle, Germany

Funder

Council of Scientific and Industrial Research

Department of Biotechnology , Ministry of Science and Technology

Department of Science and Technology, Ministry of Science and Technology

Ministry of Human Resource Development

IPB Halle

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00500

Reference95 articles.

1. Industrial applications of enzyme biocatalysis: Current status and future aspects

2. Directed evolution 2.0: improving and deciphering enzyme properties

3. Directed Evolution Empowered Redesign of Natural Proteins for the Sustainable Production of Chemicals and Pharmaceuticals

4. The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication

5. How many drug targets are there?

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