A combined in silico and in vitro study on mouse Serpina1a antitrypsin-deficiency mutants-Reference-Cited by-同舟云学术

A combined in silico and in vitro study on mouse Serpina1a antitrypsin-deficiency mutants

Published:2019-05-16 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Eggenschwiler Reto^ORCID,Patronov Atanas,Hegermann Jan,Fráguas-Eggenschwiler Mariane,Wu Guangming,Cortnumme Leon,Ochs Matthias,Antes Iris,Cantz Tobias

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-44043-3.pdf

Reference45 articles.

1. Camelier, A. A. et al. Alpha-1 antitrypsin deficiency: diagnosis and treatment. J Bras Pneumol 34, 514–527 (2008).

2. Ordonez, A. et al. Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency. Hepatology 57, 2049–2060, https://doi.org/10.1002/hep.26173 (2013).

3. Tafaleng, E. N. et al. Induced pluripotent stem cells model personalized variations in liver disease resulting from alpha1-antitrypsin deficiency. Hepatology 62, 147–157, https://doi.org/10.1002/hep.27753 (2015).

4. Segeritz, C. P. et al. hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in alpha1-antitrypsin deficiency. J Hepatol, https://doi.org/10.1016/j.jhep.2018.05.028 (2018).

5. Carlson, J. A. et al. Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice. J Clin Invest 83, 1183–1190, https://doi.org/10.1172/JCI113999 (1989).

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Rosa26-LSL-dCas9-VPR: a versatile mouse model for tissue specific and simultaneous activation of multiple genes for drug discovery;Scientific Reports;2022-11-10

2. Gene Therapy in Rare Respiratory Diseases: What Have We Learned So Far?;Journal of Clinical Medicine;2020-08-08