Evaluation of site-specific homologous recombination activity of BRCA1 by direct quantitation of gene editing efficiency
Author:
Funder
MEXT | Japan Society for the Promotion of Science
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-38311-x.pdf
Reference49 articles.
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3. Prakash, R., Zhang, Y., Feng, W. & Jasin, M. Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins. Cold Spring Harb. Perspect. Biol. 7, a016600 (2015).
4. Sawyer, S. L. et al. Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype. Cancer Discov 5, 135–142 (2015).
5. Martins, F. C. et al. Evolutionary pathways in BRCA1-associated breast tumors. Cancer Discov 2, 503–511 (2012).
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