Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis-Reference-Cited by-同舟云学术

Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis

Published:2019-04-24 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Simonin Juliette,Bille Emmanuelle,Crambert Gilles,Noel Sabrina,Dreano Elise,Edwards Aurélie,Hatton Aurélie,Pranke Iwona,Villeret Bérengère,Cottart Charles-Henry,Vrel Jean-Patrick,Urbach Valérie^ORCID,Baatallah Nesrine,Hinzpeter Alexandre,Golec Anita,Touqui Lhousseine,Nassif Xavier,Galietta Luis J. V,Planelles Gabrielle,Sallenave Jean-Michel,Edelman Aleksander,Sermet-Gaudelus Isabelle

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-42751-4.pdf

Reference40 articles.

1. Pezzulo, A. A. et al. Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature 487, 109–113 (2012).

2. Smith, J. J., Travis, S. M., Greenberg, E. P. & Welsh, M. J. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 85, 229–236 (1996).

3. Cohen, T. S. & Prince, A. Cystic fibrosis: a mucosal immunodeficiency syndrome. Nat. Med. 18, 509–519 (2012).

4. Sly, P. D. et al. Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening. Am. J. Respir. Crit. Care Med. 180, 146–152 (2009).

5. Tang, X. X. et al. Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing. J. Cell. Physiol. 227, 3887–3894 (2012).

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