Cancer cell killing by target antigen engagement with engineered complementary intracellular antibody single domains fused to pro-caspase3
Author:
Funder
RCUK | Medical Research Council
Wellcome Trust
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-44908-7.pdf
Reference35 articles.
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3. Tanaka, T., Sewell, H., Waters, S., Phillips, S. E. & Rabbitts, T. H. Single domain intracellular antibodies from diverse libraries: emphasizing dual functions of LMO2 protein interactions using a single VH domain. The Journal of biological chemistry 286, 3707–3716, https://doi.org/10.1074/jbc.M110.188193 (2011).
4. Sewell, H. et al. Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex. Scientific reports 4, 3643, https://doi.org/10.1038/srep03643 (2014).
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