Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep08047.pdf
Reference47 articles.
1. Chambers, J. W., Howard, S. & LoGrasso, P. V. Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo. J Biol Chem 288, 1079–1087; 10.1074/jbc.M112.421354 (2013).
2. Chambers, J. W. et al. Small Molecule c-jun-N-terminal Kinase (JNK) Inhibitors Protect Dopaminergic Neurons in a Model of Parkinson's Disease. ACS Chem Neurosci 2, 198–206; 10.1021/cn100109k (2011).
3. Crocker, C. E. et al. JNK Inhibition Protects Dopamine Neurons and Provides Behavioral Improvement in a Rat 6-Hydroxydopamine Model of Parkinson's Disease. ACS Chem. Neurosci. 2, 207–212; 10.1021/cn1001107 (2011).
4. Feng, Y. et al. A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases. ACS Chem Biol 8, 1747–1754; 10.1021/cb3006165 (2013).
5. Hunot, S. et al. JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A 101, 665–670 (2004).
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