Gout treatment: when a tablet is not enough
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://www.nature.com/articles/nrrheum.2013.173-c1.pdf
Reference11 articles.
1. Perez-Ruiz, F. & Herrero-Beites, A. M. Environment and genetics in gout: a maze for clinicians? Nat. Rev. Rheumatol. 10, 8–9 (2014).
2. Zhu, Y., Zhang, Y. & Choi, H. K. The serum urate-lowering impact of weight loss among men with a high cardiovascular risk profile: the Multiple Risk Factor Intervention Trial. Rheumatology (Oxford) 49, 2391–2399 (2010).
3. Dessein, P. H., Shipton, E. A., Stanwix, A. E., Joffe, B. I. & Ramokgadi, J. Beneficial effects of weight loss associated with moderate calorie/carbohydrate restriction, and increased proportional intake of protein and unsaturated fat on serum urate and lipoprotein levels in gout: a pilot study. Ann. Rheum. Dis. 59, 539–543 (2000).
4. Rock, K. L., Kataoka, H. & Lai, J. J. Uric acid as a danger signal in gout and its comorbidities. Nat. Rev. Rheumatol. 9, 13–23 (2013).
5. Zhang, W. et al. EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann. Rheum. Dis. 65, 1312–1324 (2006).
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1. Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis;Journal of Medicinal Chemistry;2019-11-30
2. 4-(2-(4-chlorophenyl)-1-((4-chlorophenyl)amino)ethyl)benzene-1, 3-diol is a potential agent for gout therapy as a dual inhibitor of XOD and NLRP3;Phytomedicine;2018-03
3. Gout treatment—more tablets might be needed;Nature Reviews Rheumatology;2014-01-28
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