Intracellular drug bioavailability: a new predictor of system dependent drug disposition
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep43047.pdf
Reference84 articles.
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4. Menochet, K., Kenworthy, K. E., Houston, J. B. & Galetin, A. Simultaneous assessment of uptake and metabolism in rat hepatocytes: a comprehensive mechanistic model. J Pharmacol Exp Ther 341, 2–15 (2012).
5. Chien, H. C. et al. Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells. Drug Metab Dispos 44, 356–364 (2016).
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