Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver-Reference-Cited by-同舟云学术

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

Published:2013-04-10 Issue:1 Volume:94 Page:126-141
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:
Short-container-title:Clin Pharmacol Ther

Author:

Chu X,Korzekwa K,Elsby R,Fenner K,Galetin A,Lai Y,Matsson P,Moss A,Nagar S,Rosania G R,Bai J P F,Polli J W,Sugiyama Y,Brouwer K L R

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference75 articles.

1. The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery

2. Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans

3. Drug Transporters in Drug Efficacy and Toxicity

4. In Vitro Inhibition of the Bile Salt Export Pump Correlates with Risk of Cholestatic Drug-Induced Liver Injury in Humans

5. Hepatic and Intestinal Drug Transporters: Prediction of Pharmacokinetic Effects Caused by Drug-Drug Interactions and Genetic Polymorphisms

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