Aneuploidy in mammalian oocytes and the impact of maternal ageing
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
https://www.nature.com/articles/s41580-022-00517-3.pdf
Reference233 articles.
1. Gruhn, J. R. et al. Chromosome errors in human eggs shape natural fertility over reproductive life span. Science 365, 1466–1469 (2019). Aneuploidy rates in human oocytes exhibit a U-shaped relationship with respect to maternal age where chromosomes and the types of errors they experience are revealed to be different in young and older oocytes.
2. Hou, Y. et al. Genome analyses of single human oocytes. Cell 155, 1492–1506 (2013).
3. Ottolini, C. S. et al. Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates. Nat. Genet. 47, 727–735 (2015). First identification of the ‘reverse segregation’ type error in human oocytes, when the sister chromatids of a bivalent separate like in mitosis during meiosis I.
4. Bell, A. D. et al. Insights into variation in meiosis from 31,228 human sperm genomes. Nature 583, 259–264 (2020).
5. Lu, S. et al. Probing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencing. Science 338, 1627–1630 (2012).
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