Abstract
AbstractAcoustic wave resonators are promising candidates for gravimetric biosensing. However, they generally suffer from strong acoustic radiation in liquid, which limits their quality factor and increases their frequency noise. This article presents an acoustic radiation-free gravimetric biosensor based on a locally resonant surface phononic crystal (SPC) consisting of periodic high aspect ratio electrodes to address the above issue. The acoustic wave generated in the SPC is slower than the sound wave in water, hence it prevents acoustic propagation in the fluid and results in energy confinement near the electrode surface. This energy confinement results in a significant quality factor improvement and reduces frequency noise. The proposed SPC resonator is numerically studied by finite element analysis and experimentally implemented by an electroplating-based fabrication process. Experimental results show that the SPC resonator exhibits an in-liquid quality factor 15 times higher than a conventional Rayleigh wave resonator at a similar operating frequency. The proposed radiation suppression method using SPC can also be applied in other types of acoustic wave resonators. Thus, this method can serve as a general technique for boosting the in-liquid quality factor and sensing performance of many acoustic biosensors.
Funder
Qatar National Research Fund
Publisher
Springer Science and Business Media LLC
Subject
Electrical and Electronic Engineering,Industrial and Manufacturing Engineering,Condensed Matter Physics,Materials Science (miscellaneous),Atomic and Molecular Physics, and Optics
Reference31 articles.
1. Gaudin, V. Advances in biosensor development for the screening of antibiotic residues in food products of animal origin–a comprehensive review. Biosens. Bioelectron. 90, 363–377 (2017).
2. Metkar, S. K. & Girigoswami, K. Diagnostic biosensors in medicine–a review. Biocatal. Agric. Biotechnol. 17, 271–283 (2019).
3. Khan, M., Hasan, M., Hossain, S., Ahommed, M. & Daizy, M. Ultrasensitive detection of pathogenic viruses with electrochemical biosensor: state of the art. Biosens. Bioelectron. 166, 112431 (2020).
4. Casadio, S. et al. Development of a novel flexible polymer-based biosensor platform for the thermal detection of noradrenaline in aqueous solutions. Chem. Eng. J. 315, 459–468 (2017).
5. Khansili, N., Rattu, G. & Krishna, P. M. Label-free optical biosensors for food and biological sensor applications. Sens. Actuators B: Chem. 265, 35–49 (2018).
Cited by
20 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献