Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques-Reference-Cited by-同舟云学术

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Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques

Published:2017-08-03 Issue:10 Volume:24 Page:640-648
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Gombash S E,Cowley C J,Fitzgerald J A,Lepak C A,Neides M G,Hook K,Todd L J,Wang G-D,Mueller C,Kaspar B K,Bielefeld E C,Fischer A J,Wood J D,Foust K D

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.nature.com/articles/gt201772.pdf

Reference56 articles.

1. Gombash SE, Cowley CJ, Fitzgerald JA, Hall JC, Mueller C, Christofi FL et al. Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice. Front Mol Neurosci 2014; 7: 81.

2. Benskey MJ, Kuhn NC, Galligan JJ, Garcia J, Boye SE, Hauswirth WW et al. Targeted Gene Delivery to the Enteric Nervous System Using AAV: A Comparison Across Serotypes and Capsid Mutants. Mol Ther 2015; 23: 488–500.

3. Buckinx R, Van Remoortel S, Gijsbers R, Waddington SN, Timmermans JP . Proof-of-concept: neonatal intravenous injection of adeno-associated virus vectors results in successful transduction of myenteric and submucosal neurons in the mouse small and large intestine. Neurogastroenterol Motil 2016; 28: 299–305.

4. Ojala DS, Amara DP, Schaffer DV . Adeno-associated virus vectors and neurological gene therapy. Neuroscientist 2015; 21: 84–98.

5. Weinberg MS, Samulski RJ, McCown TJ . Adeno-associated virus (AAV) gene therapy for neurological disease. Neuropharmacology 2013; 69: 82–88.

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