Proof-of-concept: neonatal intravenous injection of adeno-associated virus vectors results in successful transduction of myenteric and submucosal neurons in the mouse small and large intestine-Reference-Cited by-同舟云学术

Proof-of-concept: neonatal intravenous injection of adeno-associated virus vectors results in successful transduction of myenteric and submucosal neurons in the mouse small and large intestine

Published:2015-11-12 Issue:2 Volume:28 Page:299-305
ISSN:1350-1925
Container-title:Neurogastroenterology & Motility
language:en
Short-container-title:Neurogastroenterol. Motil.

Author:

Buckinx R.¹^ORCID,Van Remoortel S.¹,Gijsbers R.²³,Waddington S. N.⁴⁵,Timmermans J.-P.¹

Affiliation:

1. Laboratory of Cell Biology and Histology; Department of Veterinary Sciences; University of Antwerp; Antwerp Belgium

2. Laboratory for Viral Vector Technology & Gene Therapy; Department of Pharmaceutical and Pharmacological Sciences; KU Leuven; Leuven Belgium

3. Leuven Viral Vector Core; KU Leuven; Leuven Belgium

4. Gene Transfer Technology Group; Institute for Women's Health; University College London; London UK

5. Wits/SAMRC Antiviral Gene Therapy Research Unit; Faculty of Health Sciences; University of the Witwatersrand; Johannesburg South Africa

Funder

Fonds Wetenschappelijk Onderzoek

Medical Research Council

Publisher

Wiley

Subject

Gastroenterology,Endocrine and Autonomic Systems,Physiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/nmo.12724/fullpdf

Reference19 articles.

1. Viral vectors for gene delivery to the central nervous system;Lentz;Neurobiol Dis,2012

2. Biology of adeno-associated viral vectors in the central nervous system;Murlidharan;Front Mol Neurosci,2014

3. Adeno-Associated Virus (AAV) Vectors in the CNS;McCown;Curr Gene Ther,2011

4. Intravenous administration of AAV2/9 to the fetal and neonatal mouse leads to differential targeting of CNS cell types and extensive transduction of the nervous system;Rahim;FASEB J,2011

5. Biodistribution of adeno-associated virus serotype 9 (AAV9) vector after intrathecal and intravenous delivery in mouse;Schuster;Front Neuroanat,2014

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