Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell-Reference-Cited by-同舟云学术

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell

Published:2016-04-05 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Chattopadhyay Anasuya,O’Connor Cornelius J.,Zhang Fengzhi,Galvagnion Celine,Galloway Warren R. J. D.,Tan Yaw Sing,Stokes Jamie E.,Rahman Taufiq,Verma Chandra,Spring David R.,Itzhaki Laura S.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep23732.pdf

Reference32 articles.

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2. Yuan, C. et al. Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure–function relationship. Biochemistry 43, 12152–12161 (2004).

3. Dawson, S., Higashitsuji, H., Wilkinson, A. J., Fujita, J. & Mayer, R. J. Gankyrin: a new oncoprotein and regulator of pRb and p53. Trends Cell Biol. 16, 229–233 (2006).

4. Li, H. et al. Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma. Gastroenterology 128, 2029–2041 (2005).

5. Meng, Y. et al. Gankyrin promotes the proliferation of human pancreatic cancer. Cancer Lett. 297, 9–17 (2010).

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