Potential novel antibiotics from HTS targeting the virulence-regulating transcription factor, VirF, from Shigella flexneri-Reference-Cited by-同舟云学术

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Potential novel antibiotics from HTS targeting the virulence-regulating transcription factor, VirF, from Shigella flexneri

Published:2014-02-19 Issue:5 Volume:67 Page:379-386
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Emanuele Anthony A,Adams Nancy E,Chen Yi-Chen,Maurelli Anthony T,Garcia George A

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja201410.pdf

Reference34 articles.

1. Kumarasamy, K. K. et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect. Dis. 10, 597–602 (2010).

2. Lewis, K. Platforms for antibiotic discovery. Nat. Rev. Drug Discov. 12, 371–387 (2013).

3. Jenssen, W. D., Thakker-Varia, S., Dubin, D. T. & Weinstein, M. P. Prevalence of macrolides-lincosamides-streptogramin B resistance and erm gene classes among clinical strains of Staphylococci and Streptococci. Antimicrob. Agents Chemother. 31, 883–888 (1987).

4. Marty, F. M. et al. Emergence of a clinical daptomycin-resistant Staphylococcus aureus isolate during treatment of methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis. J. Clin. Microbiol. 44, 595–597 (2006).

5. Petrella, S. et al. Genetic basis for natural and acquired resistance to the diarylquinoline R207910 in Mycobacteria. Antimicrob. Agents Chemother. 50, 2853–2856 (2006).

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